Model-based prediction of sequence alignment quality
نویسندگان
چکیده
منابع مشابه
Model-based prediction of sequence alignment quality
MOTIVATION Multiple sequence alignment (MSA) is an essential prerequisite for many sequence analysis methods and valuable tool itself for describing relationships between protein sequences. Since the success of the sequence analysis is highly dependent on the reliability of alignments, measures for assessing the quality of alignments are highly requisite. RESULTS We present a statistical mode...
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متن کاملThe effect of sequence quality on sequence alignment
MOTIVATION The nucleotide sequencing process produces not only the sequence of nucleotides, but also associated quality values. Quality values provide valuable information, but are primarily used only for trimming sequences and generally ignored in subsequent analyses. RESULTS This article describes how the scoring schemes of standard alignment algorithms can be modified to take into account ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2008
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btn414